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This chapter is about the use of object databases in bioinformatics, and seeks to make clear where object databases can be used effectively with biological data. There has been widespread experimentation with object databases in bioinformatics for most of the history of object databases, both in support of public information resources and for use with tightly coupled analyses. This chapter focuses principally on the use of object databases in analysis-oriented biological applications, and reports on experiences using an ODMG-compliant object database with a number of genomic information resources. Object databases have generally been associated with challenging applications, for which relational databases were considered inappropriate because of limitations relating to their modeling facilities, programming interfaces, or performance. Scientific applications, including those that involve the storage of information relating to molecular biology, are typical of the sorts of applications for which relational systems are sometimes felt to be unsuitable. Bioinformatics is the use of computational techniques for the storage, analysis, sharing, and presentation of information from biology, and in particular, molecular biology [Attwood 1999]. As such, the principal information sources in bioinformatics relate to DNA and protein sequences, plus associated experimental data on the structure and function of proteins. For many years there has been exponential growth in the amount of sequence information available, a trend that is continuing as the complete genome sequences of organisms have started to be produced. Complete genome sequences, and novel experimental techniques that provide insights into the biological behavior of complete cells, are making available new information resources that promise to further increase the role of bioinformatics in important areas such as drug discovery in the pharmaceutical industry. 329 asp.net code 128 reader C# Code 128 Reader SDK to read, scan Code 128 in C#.NET class ...
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